L-Glycine : Benefits, Side Effects And More


With a quick google search on L-Glycine, the first thing you’ll see is its mother compound, Glycine. Although they sound almost the same, there is a significant difference between the two.

Glycine is an Amino Acid that your body naturally produces, clearly because it has multiple health benefits for you. You can also find this naturally in various products that are known to be great for your health. Some of these products are meat, eggs, fish, and other protein-rich foods. You can also find Glycine in your common household non-food products like cosmetics and even your pet’s favorite food!

L-Glycine is derived from Glycine. This means that although these two may have the same molecular formula, they have different arrangements compared to each other. This may lead to a difference in chemical properties, but that’s not really the case for Glycine and L-Glycine, both of which are quite similar in properties as well.

This guide will take you through everything you need to know about L-Glycine. Namely, the factors this piece will explore are uses, benefits, side effects, customer reviews, consumption and dosage, and a lot more!

About L-Glycine :

L-Glycine is an Amino Acid that is free of complexity that other compounds or naturally produced chemicals contain. Medical science spent a considerable amount of time overlooking this acid full of wonders. However, in recent times, L-Glycine has been tested for its benefits rigorously and is now sold by tons of retailers across the world. These retailers, consumers, and health care professionals really vouch for its benefits.

We know health when we know sickness. So the best way to understand the benefits of L-Glycine is to know what happens when there’s a deficiency of it.

1. Poor Brain Health

Lack of L-Glycine in the body is associated with poor brain health by causing oxidative stress. This means your memory power may decrease, you will feel more tired and suffer from fatigue, you’ll get ill more often, and have a general feeling of laziness and exhaustion dominate your mind. Your hair and skin health can also get affected by this. Oxidative stress causes grey hair and wrinkles.

2. Higher risk of Type 2 Diabetes

L-Glycine is an ideal aid to reduce the body’s resistance to insulin. Naturally, this can be applied to those who already suffer from Type 2 Diabetes. It is recommended you increase your body’s L-Glycine levels in case you suffer from this as it will facilitate acceptance of insulin.

3. Lack of other compounds in your body

L-Glycine is used by your body to make some necessary compounds for your body, one of which is Collagen. Similarly, your body needs L-Glycine to take Creatine. Collagen is one of the most important proteins for your skin’s health, which you may also find in almost every skincare supplement on the market. For those looking to bulk up, Creatine is usually the answer to your problem. It is an important ingredient found in most health care supplements that help you increase muscle mass.

4. Your muscle mass might go to waste

With a deficiency of L-Glycine in your body, it is important to know that muscle mass conservation may not occur. Multiple clinical trials have studied the effects of L-Glycine on conserving and even facilitating an increase in muscle mass.

L-Glycine Dosage :

The daily recommended dosage for L-Glycine depends on your age, body type, conditions, and more.

  • L-Glycine is quite suitable for consumption if you’re old. This is because your body’s ability to naturally produce what it needs keeps decreasing with age.
  • You may also want to consume L-Glycine if you have a deficiency. You can easily find that out through your health care professional or if you have any L-Glycine deficiency symptoms.
  • If you’re a vegetarian or a vegan who is looking for sources of protein that are friendly for you, L-Glycine is a great option.

Where can we find L-Glycine:

Now that you know what L-Glycine is and how important it is for your body, you may want to know what form to consume it in. Whether you’re a skincare enthusiast or a gym freak, this compound can be found in multiple products for you in your favorite form of consumption.

You can find L-Glycine in-

  • Your favorite foods that are a great source of protein such as meats and pulses
  • Fitness supplements that focus on muscle mass retention, bulking, and recovery
  • Supplements that help reduce stress, increase brain power, and more
  • Supplements that provide you with energy, decrease fatigue and get rid of exhaustion and tiredness
  • Skin care products such as anti-aging and hydrating creams or serums
  • You can find L-Glycine in Collagen supplements as well. This is because L-Glycine is used to naturally produce Collagen in the body.

Benefits from L-Glycine

The uses or benefits of L-Glycine are quite popular. Let’s have a look at some of these!

  • L-Glycine contains antioxidant properties that facilitate anti-aging, skincare, and brain health, and actively helps fight diseases by protecting cell health.
  • L-Glycine is full of aerobic benefits that will come in handy for you in your gym sessions or athletic performances. The compound helps maximize the benefits of physical exercise and retains its effects.
  • L-Glycine helps create various compounds such as Collagen that are good for your body. They facilitate all the functions mentioned, such as their effects on brain health and physical health.
  • Actively fights against diabetes and even helps manage symptoms. An increase in acceptance of insulin and reduction of sugar levels in the body can be facilitated through L-Glycine
  • L-Glycine significantly improves your sleep quality and enables you to get proper rest. It also reduces the concentration of alcohol in your body post-consumption, which is great for your liver’s health.
  • L-Glycine helps fight some serious diseases by supporting your extracellular matrix. Prevention of Diabetes, Cardiac Diseases or Strokes, Schizophrenia, Viral infections, and even reductions in the severity of diseases like Coronavirus has been clinically tested and proven.
  • L-Glycine is good at what it does. Your body’s mechanical system is facilitated through its use. The anti-inflammatory properties of the compound enable a much stronger immune system, faster metabolism, and better use of nutrients.

You may use L-Glycine under the recommendations of dosage from your health care physician if you feel like you may have any issues mentioned above. A recommendation is encouraged because of some possible side effects or cons you may bear the brunt of, in case you indulge in an overdose or overconsumption of the compound.

Side effects and cons associated with the use of L-Glycine

The side effects of L-Glycine can be mild, if you indulge in an overdose, especially on an empty stomach. Here are some symptoms you may feel-

  • Abdominal pain
  • Cramps
  • Digestive issues
  • Diarrhea
  • Nausea
  • Puking
  • Drowsiness

These aren’t serious symptoms at all. They’re simply mild side effects caused by overconsumption.

You should also not consume L-Glycine if-

  • You’re a child
  • You’re pregnant
  • You’re breastfeeding
  • You have got a serious disease that affects your liver and kidneys

In case of any other serious medical issue, you should contact your healthcare physician to ensure that L-Glycine is safe for consumption for you.


If you’re taking antipsychotic medications or any other medications that help with serious mental health issues or problems, make sure that you take the consultation of your healthcare professional before indulging in the consumption of L-Glycine. This is because L-Glycine interacts with some drugs and can cause harmful side effects.

Our final verdict

  • L-Glycine is an important protein for your body. It is clinically proven that it works, and you should definitely consume foods that contain this compound.
  • All you need to ensure before indulging in its consumption is that you have a deficiency, have the approval of your healthcare professional, and aren’t pregnant or breastfeeding. You should also keep this strictly out of reach of children.
  • You should also ensure that you have an appropriate dosage of L-Glycine since you may already be deriving a significant amount of it from your daily diet.
  • You can consume L-Glycine in oral capsule or tablet form, sold by dependable retailers. Make sure that you go through customer reviews to develop some faith in the company.
  • It is also important that you go through the ingredient list of the product you plan on using, especially given that you could be allergic to some extra ingredients in there.
  • Lastly, make sure that you coordinate your intake of L-Glycine with any other supplement or medicine that you may be consuming, as it could potentially lead to some side effects. We recommend you do so under your physician’s consultancy. 
  • In case you don’t consume L-Glycine for any reason, you can always consume supplements that contain Collagen.


Which benefits of L-Glycine are and are not scientifically and clinically proven?

L-Glycine has some incredible claims that almost everyone believes and most vouch for its effects. However, it is important to note that out of all these claims, only some of these are scientifically and clinically proven.
Here are the scientifically proven benefits of L-Glycine-
Anti-inflammatory in nature
Anti-Oxidant in nature
Great source of protein
Helps with sleep
Facilitates the production of Creatine and other compounds that are important for the human body
Actively fights viruses that penetrate the human body
Facilitates better immunity and health
          Here are the unsubstantiated claims-
               a. Helps with Schizophrenia
               b. Helps prevent your liver from toxins like alcohol
               c. Prevents cellular dysfunction 
          It is important to note that most of the scientific trials have actually been
          conducted on rodents and not humans.

What are some symptoms of L-Glycine deficiency?

L-Glycine deficiency can very easily happen if you’re not consuming enough amount of it from your diet or avoiding foods that are rich in protein. Here are some symptoms of deficiency to watch out for-
Fatigue, Tiredness, or Exhaustion
Irregular weight fluctuations
Urinary problems
If you have Type 2 diabetes, you may want to get checked for deficiency

L-Glycine vs Glycine- Which should I consume?

You don’t need to choose between L-Glycine and Glycine, as both of them will derive the same benefits for you. Both are major sources of protein for the body and have the same effects on it as well.
In terms of consumption, it is much easier for you to consume L-Glycine as it is more commonly found in various healthcare products, supplements, and skincare products.

Does L-Glycine help with weight loss?

L-Glycine helps with an increase in insulin levels in the body, something which is scientifically proven through clinical trials and research. If you combine your use of L-Glycine with a daily routine of exercise and a good diet, there’s a huge chance you will lose a significant amount of weight.
It is important to understand that many reliable health supplements in the market that focus on achieving fitness goals contain L-Glycine for these benefits.
However, too much intake of L-Glycine can have severe impacts on your health, including a spike in insulin levels which can lead to weight gain.

What foods are high in L-Glycine?

Meats like Turkey, Pork, Red Meat, bone broth or soups, and more
Vegetables like pulses, beans, and more. Also greens like Spinach, Asparagus, and Seaweed
Seeds and nuts like Pumpkin seeds, Sesame seeds, Carob seeds, and Pistachio
L-Glycine is a derivative of Amino Acid and an incredible source of protein for your body. This compound works best if you take it before sleeping, as it can facilitate an appropriate amount of rest for you, leaving you completely refreshed for the next day. You should also remember to not take L-Glycine on an empty stomach as it can make you feel a little dizzy.
The bottom line is, that you should definitely indulge in the consumption of L-Glycine if for some reason your body can’t seem to complete these requirements from your daily diet. L-Glycine is great for your brain, your skin, and your body!

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